Research interest

We are interested in rodent cortical and hippocampal neuron-glia microcircuitry. We use in vivo methods to assess glial cells' (mostly astrocytes) functions in active neural circuitries. Our particular interest is how glial cells contribute to memory formation and learning ability (if at all). Our techniques include intracellular recording, multi-channel extracellular recording, and optical imaging with a two-photon microscope. The followings are some of our featured research projects.

RIKEN NEWS (2016 September) 研究最前線 グリア細胞”アストロサイト”は脳内で何をしている?(Japanese)
Press release (2016 July) Glycogen distribution in the mouse brain
Press release (2016 March) In vivo tDCS astrocyte calcium depression synaptic plasticity findings
Press release (2016 March) In vivo tDCS astrocyte calcium depression synaptic plasticity findings. Featured in Japan Neurosicence Society Research Topics.
Press release (2013 April) Environmental enrichment in vivo hippocampal gamma and asymmetry findings
Research Highlight (2012 May) In vivo NBM acetylcholine cortex astrocyte calcium synaptic plasticity astrocyte membrane potential findings
Press release (2011 December) In vivo NBM acetylcholine cortex astrocyte calcium plasticity findings
Research Highlight (2009 March) S100B RAGE astrocyte vs. in vivo hippocampal (kainate) gamma findings

BioResource

BAC-GLT1-G-CaMP7 #817 (also known as G7NG817)

BAC-GLT1-G-CaMP7 #817 (also known as G7NG817) transgenic mouse is distributed through RIKEN BioResource Center. The Resource ID is RBRC09650. The mice are being bred for distribution.

BAC-CACNG5-GFP #500

BAC-CACNG5-GFP transgenic mouse is distributed through RIKEN BioResource Center. The Resource ID is RBRC06258.

Software

Pulsedecci software (Pulse / square wave) generator with optional trigger input for Raspbery Pi and some random drawings of neurons & glia.